leukotrienes

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• leukotrienes — (= LTA4, LTB4, LTC4, LTD4, LTE4) A family of hydroxyeicosatetraenoic (HETE) acid derivatives. LTA4 and LTB4 are modified lipids; leukotrienes C, D and E have the lipid conjugated to glutathione (LTC4) or cysteine (LTD 4, LTE4) to form the… …   Dictionary of molecular biology

• leukotrienes — Products of eicosanoid metabolism (usually, arachidonic acid) with postulated physiologic activity such as mediators of inflammation and roles in allergic reactions; they differ from the related prostaglandins and thromboxanes by not having a… …   Medical dictionary

• Leukotriene — Leukotrienes are naturally produced eicosanoid lipid mediators, which may be responsible for the effects of an inflammatory response. Leukotrienes use both autocrine signalling and paracrine signalling to regulate the body s response.… …   Wikipedia

• Eicosanoid — In biochemistry, eicosanoids are signaling molecules made by oxygenation of twenty carbon essential fatty acids, (EFAs).They exert complex control over many bodily systems, mainly in inflammation or immunity, and as messengers in the central… …   Wikipedia

• drug — drug1 /drug/, n., v., drugged, drugging. n. 1. Pharm. a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well being. 2. (in federal law) a. any substance… …   Universalium

• Drug — /droog/, n. Zoroastrianism. the cosmic principle of disorder and falsehood. Cf. Asha. [ < Avestan drauga] * * * I Any chemical agent that affects the function of living things. Some, including antibiotics, stimulants, tranquilizers,… …   Universalium

• Eicosanoid biosynthesis — Eicosanoids are signaling molecules, synthesized by most living creatures. (The IUPAC and the IUBMB use the equivalent term Icosanoid.cite web author=Cyberlipid Center| title=Prostanoids url= http://www.cyberlipid.org/prost1/pros0001.htm#9 |… …   Wikipedia

• Hepoxilin — Chembox new ImageFile=Hepoxilin A3.png ImageSize= Name=Hepoxilin A3 IUPACName=(5E,9E) 8 hydroxy 10 [3 [(E) oct 2 enyl] 2 oxiranyl] deca 5,9 dienoic acid OtherNames= HXA3 Section1= Chembox Identifiers CASNo= PubChem=5353666… …   Wikipedia

• Cysteinyl leukotriene receptor 2 — Identifiers Symbols CYSLTR2; CYSLT2; CYSLT2R; HG57; HPN321; KPG 011; hGPCR21 External IDs …   Wikipedia

• antileukotriene — A drug that prevents or alleviates bronchoconstriction in asthma by blocking the production or action of naturally occurring leukotrienes; may also be useful in psoriasis.In 1940 a naturally occurring mediator of asthmatic bronchoconstriction,… …   Medical dictionary

• Arachidonate 5-lipoxygenase — (5 lipoxygenase, 5 LO or Alox5) is a human enzyme, member of the lipoxygenase family. It transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases.ubstrates and productsEFA substrates and… …   Wikipedia