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1 кининогены
полифункциональные гликопротеиды, молекулы которых представлены одной полипептидной цепью, синтезируются в основном гепатоцитами и перед секретированием в кровоток подвергаются посттрансляционному гликозилированию. К. под действием кининогенинов (см. кининогенины) превращаются в кинины (см. кинины). В плазме крови человека присутствуют два К.: низкомолекулярный и высокомолекулярный. Оба кининогена связываются с различными клетками крови и участвуют в регуляции артериального давления, модулируют воспалительные и антитромбические реакции, создают важную регуляторную систему взаимодействия плазменных белков с клетками крови и клетками сосудистой стенки.Толковый биотехнологический словарь. Русско-английский. > кининогены
См. также в других словарях:
Kininogen — Kininogens are proteins that are defined by their role as precursors for kinin, but that also can have additional roles. The two main types are: * High molecular weight kininogen, which is produced by the liver together with prekallikrein. It… … Wikipedia
Cystatin — Proteinase inhibitor I25, cystatin Crystal structure of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata.[1] … Wikipedia
High-molecular-weight kininogen — (HMWK), also known as the Williams Fitzgerald Flaujeac factor or the Fitzgerald factor or the HMWK kallikrein factor, is a protein from the blood coagulation system as well as the kinin kallikrein system. It is a protein that adsorbs to the… … Wikipedia
Low-molecular-weight kininogen — is a form of kininogen, which has been identified in mice, [cite journal |author=Shesely E, Hu C, Alhenc Gelas F, Meneton P, Carretero O |title=A second expressed kininogen gene in mice |journal=Physiol Genomics |volume=26 |issue=2 |pages=152–7… … Wikipedia
CAPN1 — Calpain 1, (mu/I) large subunit, also known as CAPN1, is a human gene.cite web | title = Entrez Gene: CAPN1 calpain 1, (mu/I) large subunit| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=823| accessdate =… … Wikipedia
kinin — One of a number of widely differing substances having pronounced and dramatic physiologic effects. Some ( e.g., kallidin and bradykinin) are polypeptides, formed in blood by proteolysis secondary to some pathological process, that stimulate… … Medical dictionary
Chromosome — For a non technical introduction to the topic, see Introduction to genetics. Diagram of a replicated and condensed metaphase eukaryotic chromosome. (1) Chromatid – one of the two identical parts of the chromosome after S phase. (2)… … Wikipedia
Kinin-kallikrein system — The kinin kallikrein system or simply kinin system is a poorly delineated system of blood proteins that plays a role in inflammation, blood pressure control, coagulation and pain. Its important mediators bradykinin and kallidin are vasodilators… … Wikipedia
Cystatin C — PDB rendering based on 1r4c … Wikipedia
CAPN2 — Calpain 2, (m/II) large subunit, also known as CAPN2, is a human gene. PBB Summary section title = summary text = The calpains, calcium activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains… … Wikipedia
AHSG — Alpha 2 HS glycoprotein, also known as AHSG, is a human gene.cite web | title = Entrez Gene: AHSG alpha 2 HS glycoprotein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=197| accessdate = ] PBB Summary… … Wikipedia
