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NHEJ

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  • Non-homologous end joining — (NHEJ) is a pathway that repairs double strand breaks in DNA. NHEJ is referred to as non homologous because the break ends are directly ligated without the need for a homologous template, in contrast to homologous recombination, which requires a… …   Wikipedia

  • DNA repair — For the journal, see DNA Repair (journal). DNA damage resulting in multiple broken chromosomes DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human… …   Wikipedia

  • Homology directed repair — (HDR) is a mechanism in cells to repair double strand DNA lesions. This repair mechanism can only be used by the cell when there is a homologue piece of DNA present in the nucleus, mostly in G2 and S phase of the cell cycle. When the homologue… …   Wikipedia

  • Homologous recombination — Figure 1. During meiosis, homologous recombination can produce new combinations of genes as shown here between similar but not identical copies of human chromosome 1. Homologous recombination is a type of genetic recombination in which nucleotide …   Wikipedia

  • Recombinación no homóloga — La recombinación no homóloga o unión de extremos no homólogos (cuya sigla en inglés es NHEJ) es una ruta que repara roturas en la doble hebra de ADN. Es denominada no homóloga porque los extremos rotos son directamente ligados sin la necesidad un …   Wikipedia Español

  • Ku (protein) — Ku is a protein that binds to DNA double strand break ends and is required for the non homologous end joining (NHEJ) pathway of DNA repair. Ku is evolutionarily conserved from bacteria to human. The ancestral bacterial Ku is a homodimer (two… …   Wikipedia

  • Reparación del ADN — Saltar a navegación, búsqueda Daños en el ADN, mostrados como roturas en los cromosomas. La reparación del ADN es un proceso constante en la célula, esencial para su supervivencia ya que protege al genoma de daños y mutaciones dañinas. En las… …   Wikipedia Español

  • LIG4 — is a human gene that encodes the protein DNA Ligase IV.cite web | title = Entrez Gene: LIG4 ligase IV, DNA, ATP dependent| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=3981| accessdate = ] PBB Summary… …   Wikipedia

  • Ku (proteína) — Estructura de Ku humana unida a ADN. Ku70 es mostrada en violeta, Ku80 en azul, y la hebra de ADN en verde. Ku es una proteína que se une a terminaciones quebradas de ADN de doble hebra y es necesaria para la ruta de reparación del ADN por… …   Wikipedia Español

  • DNA-PKcs — Protein kinase, DNA activated, catalytic polypeptide Identifiers Symbols PRKDC; DNA PKcs; DNAPK; DNPK1; HYRC; HYRC1; XRCC7; p350 External IDs …   Wikipedia

  • XLF (protein) — Nonhomologous end joining factor 1 Rendering based on PDB 2QM4 …   Wikipedia

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