selectable marker gene

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• marker gene — Gene that confers some readily detectable phenotype on cells carrying the gene, either in culture, or in transgenic or chimeric organisms. Gene could be an enzymic reporter gene, a selectable marker conferring antibiotic resistance, or a cell… …   Dictionary of molecular biology

• chimeric selectable marker gene — A gene that is constructed from parts of two or more different genes and allows the host cell to survive under conditions where it would otherwise die …   Glossary of Biotechnology

• Marker gene — A marker gene is a gene used in molecular biology to determine if a nucleic acid sequence has been successfully inserted into an organism s DNA. There are two types of marker genes: a selectable marker and a marker for screening. Selectable… …   Wikipedia

• Selectable marker — A selectable marker is a gene introduced into a cell, especially a bacterium or to cells in culture, that confers a trait suitable for artificial selection. They are a type of reporter gene used in laboratory microbiology, molecular biology, and… …   Wikipedia

• Selectable Marker — Als Selectable Marker wird in der Gentechnik ein Gen bezeichnet, das zusammen mit dem „gene of interest“, also dem eigentlich gewünschten Gen, in den veränderten Organismus eingebracht wird, um Individuen mit erfolgreicher Genveränderung erkennen …   Deutsch Wikipedia

• selectable marker — A gene whose expression allows the identification of a specific trait or gene in an organism …   Glossary of Biotechnology

• Gene trapping — is a high throughput approach that is used to introduce insertional mutations across the mammalian genome. It is performed with gene trap vectors whose principal element is a gene trapping cassette consisting of a promoterless reporter gene… …   Wikipedia

• dominant selectable marker — A gene that allows the host cell to survive under conditions where it would otherwise die. Synonym: positive selectable marker …   Glossary of Biotechnology

• Gene targeting — NOTOC Gene targeting (also, replacement strategy based on homologous recombination) is a genetic technique that uses homologous recombination to change an endogenous gene. The method can be used to delete a gene, remove exons, and introduce point …   Wikipedia

• Gene gun — PSD 1000/He Particle Delivery System A gene gun or a biolistic particle delivery system, originally designed for plant transformation, is a device for injecting cells with genetic information. The payload is an elemental particle of a heavy metal …   Wikipedia

• Marker assisted selection — or marker aided selection (MAS) is a process whereby a marker (morphological, biochemical or one based on DNA/RNA variation) is used for indirect selection of a genetic determinant or determinants of a trait of interest (i.e. productivity,… …   Wikipedia