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loading dose

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  • loading dose — n a large initial dose of a substance or series of such doses given to rapidly achieve a therapeutic concentration in the body * * * a dose of medication, often larger than subsequent doses, administered to establish a therapeutic level of the… …   Medical dictionary

  • Loading dose — A loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose.[1] A loading dose is most useful for drugs that are eliminated from the body… …   Wikipedia

  • Dose-response relationship — Semi log plots of two agonists with different Kd. The dose response relationship, or exposure response relationship, describes the change in effect on an organism caused by differing levels of exposure (or doses) to a stressor (usually a… …   Wikipedia

  • dose — 1. The quantity of a drug or other remedy to be taken or applied all at one time or in fractional amounts within a given period. Cf.:dosage (2). 2. In nuclear medicine, amount of energy absorbed per unit mass of irradiated material (absorbed d.) …   Medical dictionary

  • Median lethal dose — This article is about the toxicological term. For the album by Mudvayne, see L.D. 50 (album). For other uses, see LD50 (disambiguation). In toxicology, the median lethal dose, LD50 (abbreviation for “Lethal Dose, 50%”), LC50 (Lethal Concentration …   Wikipedia

  • histidine loading test — (for folic acid deficiency) a loading dose of histidine is given, and the resultant urinary excretion of excess formiminoglutamic acid (FIGLU) is measured, because that is dependent on the amount of tetrahydrofolic acid that is present. Called… …   Medical dictionary

  • Amiodarone — Systematic (IUPAC) name (2 {4 [(2 butyl 1 benzofuran 3 yl)carbonyl] …   Wikipedia

  • Warfarin — This article is about the drug with the brandname Coumadin. For the anticoagulant rodenticide poisons often called coumarins or coumadins , see 4 hydroxycoumarins. Warfarin …   Wikipedia

  • Leflunomide — drugbox IUPAC name = 5 methyl N [4 (trifluoromethyl) phenyl] isoxazole 4 carboxamide CAS number = 75706 12 6 ATC prefix = L04 ATC suffix = AA13 ATC supplemental = PubChem = 3899 DrugBank = APRD00205 C=12 | H=9 | F=3 | N=2 | O=2 molecular weight …   Wikipedia

  • Biological half-life — For other uses, see Half life (disambiguation). The biological half life or elimination half life of a substance is the time it takes for a substance (for example a metabolite, drug, signalling molecule, radioactive nuclide, or other substance)… …   Wikipedia

  • Creatine supplements — For the biochemistry and physiology of creatine, see Creatine. Creatine supplements are athletic aids used to increase high intensity athletic performance. Though researchers have known of the use of creatine as an energy source by skeletal… …   Wikipedia

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