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141 Chain, Ernst Boris
SUBJECT AREA: Medical technology[br]b. 19 June 1906 Berlin, Germanyd. 12 August 1979 Ireland[br]Anglo-German biochemist and physiologist, co-worker with Florey in the isolation of sufficient supplies of the antibiotic penicillin for clinical use during wartime.[br]Chain graduated in Berlin at the Charite Hospital in 1930. A refugee from political persecution, in 1933 he went to the School of Biochemistry in Cambridge, and in 1935 moved to the School of Pathology at Oxford. He became a British subject in 1939. His interests had involved the study of enzymes and the isolation of physiologically active substances from natural sources. In 1938 he drew Florey's attention to Fleming's note of 1929 reporting the bacterial growth inhibiting qualities of Penicillium mould. Using makeshift equipment and with little initial support, they isolated small quantities of penicillin, which they were then able to use clinically with dramatic effect.Chain had always hoped for adequate resources to develop penicillin and other antibiotics in Britain. This was not forthcoming, however, and in 1948 a research chair and institute was created for him in Rome, at the International Research Centre for Chemical Microbiology. In 1961 he returned to London to the Chair of Biochemistry at Imperial College. There, with the help of a large donation from the Wolfson Foundation, an appropriate building with facilities for the large-scale development and production of biochemical substances was finally made available. His co-equal part in the development of penicillin was recognized by the sharing of the Nobel Prize for Medicine between Florey, Fleming and himself, and he received numerous honours and honorary degrees from a large number of governments and international institutions.[br]Principal Honours and DistinctionsKnighted 1944. Nobel Prize for Medicine (jointly with H.W.Florey and A.Fleming) 1945. Fellow of the Royal Society 1949. Ehrlich Prize 1954.Bibliography1941, "Penicillin as a chemotherapeutic agent", Lancet (with Florey). 1941, "Further observations on penicillin", Lancet.1949, Antibiotics, Oxford, (with Florey et al.) MG
См. также в других словарях:
develop — de‧vel‧op [dɪˈveləp] verb 1. [intransitive, transitive] to grow or gradually change into a larger, stronger, or more advanced state: • Once a stock market develops in the Czech Republic, the bank s customers will be offered investment accounts.… … Financial and business terms
develop — de|vel|op W1S3 [dıˈveləp] v ▬▬▬▬▬▬▬ 1¦(grow)¦ 2¦(new idea/product)¦ 3¦(feeling)¦ 4¦(skill/ability)¦ 5¦(disease)¦ 6¦(fault/problem)¦ 7¦(problem/difficulty)¦ 8¦(idea/argument)¦ 9¦(land)¦ 10¦(photography)¦ … Dictionary of contemporary English
develop */*/*/ — UK [dɪˈveləp] / US verb Word forms develop : present tense I/you/we/they develop he/she/it develops present participle developing past tense developed past participle developed Get it right: develop: Don t write the ed and ing forms of develop… … English dictionary
develop — de|vel|op [ dı veləp ] verb *** ▸ 1 grow/change ▸ 2 be affected by/affect ▸ 3 improve/create ▸ 4 use land for something ▸ 5 prepare photograph 1. ) intransitive if people, animals, or plants develop, they change or grow as they get older: All… … Usage of the words and phrases in modern English
develop — v. (D; intr.) to develop from; into (to develop from a child into an adult) * * * [dɪ veləp] into (to develop from a child into an adult) (D; intr.) to develop from … Combinatory dictionary
Develop — De*vel op (d[ e]*v[e^]l [o^]p), v. t. [imp. & p. p. {Developed}; p. pr. & vb. n. {Developing}.] [F. d[ e]veloper; d[ e] (L. dis ) + OF. voluper, voleper, to envelop, perh. from L. volup agreeably, delightfully, and hence orig., to make agreeable… … The Collaborative International Dictionary of English
Develop — or Develop may refer to: NASA DEVELOP (intern program), a NASA Applied Sciences student program Develop India Group, a independent newsletter Develop (magazine), a trade publication for the video game industry develop (Apple magazine), a… … Wikipedia
From the beginnings to Avicenna — Jean Jolivet INTRODUCTION Arabic philosophy began at the turn of the second and third centuries of the Hegira, roughly the ninth and tenth centuries AD. The place and the time are important. It was in 133/750 that the ‘Abbāssid dynasty came to… … History of philosophy
Develop — De*vel op, v. i. 1. To go through a process of natural evolution or growth, by successive changes from a less perfect to a more perfect or more highly organized state; to advance from a simpler form of existence to one more complex either in… … The Collaborative International Dictionary of English
develop — 1650s, unroll, unfold, from Fr. développer, replacing English disvelop (1590s, from M.Fr. desveloper), both from O.Fr. desveloper unwrap, unfurl, unveil; reveal the meaning of, explain, from des undo + veloper wrap up, of uncertain origin,… … Etymology dictionary
develop — I verb accrue, adolescere, advance, advance in successive gradation, alere, amplify, arise from, augeri, augment, become, become apparent, begin from, bring forth, bring into being, bring to a complete condition, bring to a more advanced state,… … Law dictionary
