alkylating

См. также в других словарях:

• alkylating agent — n a substance that causes replacement of hydrogen by an alkyl group esp. in a biologically important molecule specif one with mutagenic activity that inhibits cell division and growth and is used to treat some cancers * * * a highly reactive… …   Medical dictionary

• alkylating agent — alkylating agent. См. алкилирующий агент. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

• Alkylating antineoplastic agent — An alkylating antineoplastic agent is an alkylating agent that attaches an alkyl group to DNA.Since cancer cells generally proliferate unrestrictively more than healthy cells do, cancer cells are more sensitive to DNA damage such as being… …   Wikipedia

• alkylating agent — A reagent that places an alkyl group, eg. propyl in place of a nucleophilic group in a molecule. Alkylating reagents include a number of cytotoxic drugs some of which react fairly specifically with N7 of the purine ring and lead to depurination… …   Dictionary of molecular biology

• alkylating agents — a class of drugs used in chemotherapy that includes cyclophosphamide and melphalan. These drugs bind to DNA and prevent complete separation of the two DNA chains during cell division. Side effects are those of other cytotoxic drugs; in addition,… …   The new mediacal dictionary

• alkylating — alˈkylāting adjective (of a drug) killing cells by damaging DNA and interfering with cell replication • • • Main Entry: ↑alkyl …   Useful english dictionary

• alkylating agent — noun Date: 1900 a substance that causes replacement of hydrogen by an alkyl group especially in a biologically important molecule; specifically one with mutagenic activity that inhibits cell division and growth and is used to treat some cancers …   New Collegiate Dictionary

• alkylating drug — Pharm. any of various potentially cytotoxic, carcinogenic, and mutagenic substances: used therapeutically to destroy cells, esp. proliferating cancer cells. * * * …   Universalium

• alkylating agents — a class of drugs used in chemotherapy that includes cyclophosphamide and melphalan. These drugs bind to DNA and prevent complete separation of the two DNA chains during cell division …   Medical dictionary

• alkylating agent — A class of chemicals that transfer alkyl (methyl, ethyl, etc.) groups; for example to the bases in DNA. Some of these (especially ethyl methane sulphonate, abbreviated EMS) have been much used as mutagens …   Glossary of Biotechnology

• alkylating agent — A drug that is used in the treatment of cancer. It interferes with the cell s DNA and inhibits cancer cell growth …   English dictionary of cancer terms