-
1 isoniazid
Isoniazid n, Isonicotinsäurehydrazid n, INH ( Tuberkulostatikum) -
2 isoniazid
-
3 isoniazid
мед.сущ. изониазид* * *фарм. изониазид, тубазид -
4 isoniazid
◙ n. איזוניאציד (תרכובת כימית המשמשת כתרופה לטיפול בשחפת)* * *◙ (תפחשב לופיטל הפורתכ תשמשמה תימיכ תבוכרת) דיצאינוזיא◄ -
5 isoniazid
n. 이소니아지드, 이소니코틴산 하이드라지드(항결핵제) -
6 isoniazid
n. isoniazide (chemische samenstelling dienst doende als geneesmiddel bij behandeling van tuberculosis) -
7 isoniazid
إيزونيازيد* * *إِيزونيازيد (دواء للسل) -
8 isoniazid
• hidrazid izonikotinske kiselin; izoniazid; lek protiv tuberkuloze -
9 isoniazid
-
10 isoniazid
이소니아지드 -
11 isoniazid
s.isoniacida. -
12 isoniazid polyneuropathy
Isoniazidpolyneuropathie f ( infolge Isoniazidtherapie)Fachwörterbuch Medizin Englisch-Deutsch > isoniazid polyneuropathy
-
13 isonicotinic acid hydrazide
Fachwörterbuch Medizin Englisch-Deutsch > isonicotinic acid hydrazide
-
14 INH
1) Медицина: изониазид (препарат для лечения туберкулеза)2) Военный термин: Improved Nike Hercules4) Чат: Insert Name Here5) Аэропорты: Inhambane, Mozambique -
15 inh
1) Медицина: изониазид (препарат для лечения туберкулеза)2) Военный термин: Improved Nike Hercules4) Чат: Insert Name Here5) Аэропорты: Inhambane, Mozambique -
16 Domagk, Gerhard Johannes Paul
SUBJECT AREA: Medical technology[br]b. 30 October 1895 Lagow, Brandenburg, Germanyd. 24 April 1964 Burgberg, Germany[br]German physician, biochemist and pharmacologist, pioneer of antibacterial chemotherapy.[br]Domagk's studies in medicine were interrupted by the outbreak of the First World War and his service in the Army, delaying his qualification at Kiel until 1921. For a short while he worked at the University of Greifswald, but in 1925 he was appointed Reader in Pathology at the University of Munster, where he remained as Extraordinary Professor of General Pathology and Pathological Anatomy (1928) and Professor (1958).In 1924 he published a paper on the role of the reticulo-endothelial system against infection. This led to his appointment as Director of Research by IG Farbenindustrie in their laboratory for experimental pathology and bacteriology. The planned programme of research into potential antibacterial chemotherapeutic drugs led, via the discovery of the dye Prontosil rubrum by his colleagues, to his reporting in 1936 the clinical antistreptococcal effects of the sulphonamide drugs. These results were confirmed in other countries, but owing to problems with the Nazi authorities he was unable to receive until 1947 the Nobel Prize that he was awarded in 1939.Domagk turned his interest to the chemotherapy of tuberculosis, and in 1946 he was able to report the therapeutic activity of the thiosemicarbazones, which, although too toxic for general use, in their turn led to the discovery of the potent and effective isoniazid. In his later years he moved into the field of cancer chemotherapy, but interestingly he wrote, "One should not have too great expectations of the future of cytostatic agents." His only daughter was one of the first patients to have a severe streptococcal infection successfully treated with Prontosil rubrum.[br]Principal Honours and DistinctionsNobel Prize for Medicine 1939. Foreign Member of the Royal Society. Paul Ehrlich Gold Medal.Bibliography1935, "Ein Beitrag zur Chemotherapie der bakteriellen Infektionen", Deutsche med. Woch.1924, Virchows Archiv für Path. Anat. und Physiol. u.f. klin. Med. 253:294–638.Further Reading1964, Biographical Memoirs of the Royal Society: Gerhard Domagk, London.MGBiographical history of technology > Domagk, Gerhard Johannes Paul
См. также в других словарях:
Isoniazid — Systematic (IUPAC) name isonicotinohydrazide … Wikipedia
isoniazid — ☆ isoniazid [ī′sō nī′ə zid΄, ī′sənī′ə zid΄ ] n. [ ISO + NI(COTINIC) + (HYDR)AZ(INE) + ID] an antibacterial drug, C6H7N3O, used in treating and preventing tuberculosis … English World dictionary
Isoniazid — Strukturformel Allgemeines Freiname Isoniazid Andere Namen … Deutsch Wikipedia
isoniazid — /uy seuh nuy euh zid/, n. Pharm. a white, crystalline, water soluble solid, C6H7N3O, used in the treatment of tuberculosis. [1950 55; short for ISONICOTINIC ACID HYDRAZIDE] * * * ▪ drug also called isonicotinic acid hydrazide (INH) drug… … Universalium
isoniazid — Isonicotinic acid hydrazide; first line and probably most commonly used antituberculosis drug. Organisms rapidly develop resistance against this drug if it is used alone in the treatment of active disease. Hepatic toxicity is the major side… … Medical dictionary
Isoniazid — I|so|ni|a|zid [Kurzw. aus Isonicotinsäurehydrazid], das; s: als Nicotinsäure Antimetabolit wirkendes Tuberkulosemittel. * * * Isoniazid das, s, Tuberkulostatika … Universal-Lexikon
isoniazid — isonicotinic acid hydrazide; = INH; n. a drug used in the treatment of tuberculosis, usually taken by mouth. Because tuberculosis bacteria soon become resistant to isoniazid, it is given in conjunction with other antibiotics. Occasional side… … The new mediacal dictionary
isoniazid neuropathy — polyneuropathy seen in some patients on isoniazid therapy, consisting of symmetrical numbness and paresthesias of the lower extremities … Medical dictionary
isoniazid — noun Etymology: is + nicotinic acid + hydrazide Date: 1952 a crystalline compound C6H7N3O used in treating tuberculosis … New Collegiate Dictionary
isoniazid — noun A medication used in the prevention and treatment of tuberculosis, having the chemical formula CHNO … Wiktionary
Isoniazid — Iso|ni|azi̱d [Kurzwort aus ↑Isonikotinsäurehydrazid] s; [e]s: = Isonikotinsäurehydrazid … Das Wörterbuch medizinischer Fachausdrücke