Cooperativity

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• Cooperativity — is a phenomenon displayed by enzymes or receptors that have multiple binding sites where the affinity of the binding sites for a ligand is increased, positive cooperativity, or decreased, negative cooperativity, upon the binding of a ligand to a… …   Wikipedia

• cooperativity — Phenomenon displayed by enzymes or receptors that have multiple binding sites. Binding of one ligand alters the affinity of the other site(s). Both positive and negative cooperativity are known; positive cooperativity gives rise to a sigmoidal… …   Dictionary of molecular biology

• cooperativity — /koh op euhr euh tiv i tee/, n. Biochem. the increase or decrease in the rate of interaction between a reactant and a protein as the reactant concentration increases. Also, co operativity. [COOPERATIVE + ITY] * * * ▪ enzymology       in… …   Universalium

• Cooperativity — …   Википедия

• cooperativity — noun An interaction between the substrate binding sites of an allosteric enzyme in which binding at one site increases or decreases binding at another …   Wiktionary

• cooperativity — A property of certain proteins (often enzymes) in which the binding curves or saturation curves or, in the case of enzymes, a plot of initial rates as a function of initial substrate concentration, are nonhyperbolic; suggests that the binding of… …   Medical dictionary

• cooperativity — /koh op euhr euh tiv i tee/, n. Biochem. the increase or decrease in the rate of interaction between a reactant and a protein as the reactant concentration increases. Also, co operativity. [COOPERATIVE + ITY] …   Useful english dictionary

• negative cooperativity — cooperativity in which the dissociation constant for each successive ligand bound is higher than for the one preceding it, so that the binding affinity is successively decreased …   Medical dictionary

• positive cooperativity — cooperativity in which the dissociation constant for each successive ligand bound is lower than for the one preceding it, so that the binding affinity is successively increased …   Medical dictionary

• Cooperative binding — In biochemistry, a macromolecule exhibits cooperative binding if its affinity for its ligand changes with the amount of ligand already bound. Cooperative binding is a special case of allostery. Cooperative binding requires that the macromolecule… …   Wikipedia

• Enzyme kinetics — is the study of the chemical reactions that are catalysed by enzymes, with a focus on their reaction rates. The study of an enzyme s kinetics reveals the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled,… …   Wikipedia